From Termini Station:

go out on Via Gioliti and turn right on Via Gioberti until the Santa Maria Maggiore church, take Via Merulana until Via San Martino ai Monti, turn right and the first street on the left is Via Domenichino. From the Fiumicino airport: take the direct train to Termini Station

From the Fiumicino airport:

take the bus to Anagnina metro station, take the metro and get off at Vittorio Emanuele from there take Via dello Statuto and keep on walking on Via G. Lanza and turn to the right on Via Domenichino. Shuttle: upon request a driver can pick you up and take you to both airports the cost is 45 euro and a previouse notice.